Buy 4-MeTMP (threo-4-Methylmethylphenidate)

Buy 4-MeTMP (threo-4-Methylmethylphenidate)

4‑MeTMP (threo‑4‑Methylmethylphenidate) is a phenidate research stimulant structurally related to methylphenidate, valued by laboratories for its focused profile on dopamine and noradrenaline transporters, with comparatively lower functional dopamine reuptake efficacy than its parent compound. As a specialist item at Davechemicals.com, this compound is supplied strictly for research purposes only, not for human or veterinary use, and is suited to projects investigating novel phenidate analogues, transporter binding, and structure‑activity relationships within stimulant pharmacology.

What is 4‑MeTMP (threo‑4‑Methylmethylphenidate) ❓

4‑MeTMP, also referred to as threo‑4‑Methylmethylphenidate, is a synthetic stimulant research chemical from the phenidate family, structurally related to methylphenidate, the active ingredient in many ADHD medications. It was originally explored in pharmaceutical research as a potential alternative agent in projects assessing treatments for stimulant misuse, especially where selective modulation of dopamine transporters was of interest.

In the scientific literature, 4‑MeTMP is described as having a high binding affinity at the dopamine transporter but lower efficacy as a dopamine reuptake blocker compared with methylphenidate, a contrast that makes it a useful probe for transporter function and structure‑activity work. According to a recent analysis from specialist toxicology and pharmacology groups, 4‑MeTMP is part of a wider wave of ring‑substituted methylphenidate analogues that appeared on the research chemical market after being characterised in preclinical studies.

For researchers who wish to buy 4‑MeTMP threo‑4‑Methylmethylphenidate online, our dedicated product page at Davechemicals.com provides practical information, packaging options, and secure ordering. You can view the current stock and technical overview here: buy 4‑MeTMP threo‑4‑Methylmethylphenidate.

Why Labs buy 4‑MeTMP threo‑4‑Methylmethylphenidate For Research

From an analytical and pharmacological perspective, 4‑MeTMP sits in a very interesting corner of the phenidate landscape.

Mechanistic interest for transporter studies

According to data summarised on Wikipedia’s 4‑Methylmethylphenidate entry and related pharmacology papers, 4‑MeTMP:

• Shows high affinity for the dopamine transporter, similar to standard methylphenidate.
• Displays lower efficacy in blocking dopamine reuptake than methylphenidate, which makes it less “efficient” at functionally inhibiting uptake, despite strong binding.
• Has measurable activity at the noradrenaline transporter, in line with other phenidates, although the functional profile is somewhat muted compared with more potent analogues.

The parent compound methylphenidate is well documented as a dopamine and noradrenaline reuptake inhibitor that increases synaptic monoamine levels, as detailed in DrugBank’s entry on methylphenidate and specialist pharmacology reviews. Because 4‑MeTMP retains the scaffold but shifts the functional profile, it helps researchers dissect which structural changes have the strongest influence on transporter binding versus transporter inhibition.

For labs already exploring related phenidates, compounds like 4‑Fluoromethylphenidate, 3,4‑CTMP, and other ring‑substituted analogues have been evaluated for their potency and selectivity, making 4‑MeTMP a natural addition to a comparative panel.

For research purposes only

At Davechemicals.com our stance is straightforward. 4‑MeTMP threo‑4‑Methylmethylphenidate is sold strictly as a research chemical, with no recommendation for human or animal consumption, clinical use, or any application outside controlled laboratory work. The same applies to other specialist items such as carfentanil for sale and fentanyl powder for sale, which are clearly labelled as analytical or reference materials only.

Chemical Profile of 4‑MeTMP threo‑4‑Methylmethylphenidate

Researchers often group 4‑MeTMP with other phenidates due to a shared core structure that interacts with monoamine transporters. Although detailed ADME data for 4‑MeTMP are more limited than for classical therapeutic stimulants, its parent compound methylphenidate has been thoroughly described in sources such as DrugBank and peer‑reviewed pharmacokinetic reviews.

Structural and functional context

• Class: Phenidate stimulant research chemical.
• Core structure: Piperidine‑based ester similar to methylphenidate, with a 4‑methyl substitution on the aromatic ring.
• Reported effect profile (preclinical): Lower functional potency as a dopamine reuptake inhibitor relative to methylphenidate, despite strong binding at the transporter, as described in structure‑activity studies on methylphenidate analogues.

Specialist analytical suppliers such as Cayman Chemical list (±)‑threo‑4‑Methylmethylphenidate hydrochloride as an analytical reference standard, reinforcing its role in method development and assay validation rather than any consumer‑facing purpose.

On Davechemicals.com, we follow the same approach with 4‑MeTMP, positioning it alongside targeted research products like buy 4‑MPD online, buy MDPT online TBuONE, and NPS stimulant analogues such as buy NEP online for laboratories that already operate within strict compliance frameworks.

Table 1: 4‑MeTMP vs Classic Phenidate Research Standards

This table is for research planning only and does not endorse any human use.

Where do labs buy 4‑MeTMP threo‑4‑Methylmethylphenidate online safely?

For researchers in the United Kingdom, United States, Germany, Australia, and across Asia, sourcing consistent, traceable material is more valuable than chasing the lowest advertised price. 4‑MeTMP is not a casual purchase, it is a niche research item.

At Davechemicals.com we position 4‑MeTMP threo‑4‑Methylmethylphenidate alongside other specialist research stimulants and synthetic analogues, including:

• buy methylone online for studies on substituted cathinones.
• buy eutylone online for NPS stimulant profiling.
• buy 3‑MeO‑PCP online and buy 2‑FDCK online USA for dissociative pharmacology projects.

For any order, we clearly state “for research purposes only”, and our Davechemicals.com Contact page is available if your lab needs clarification on packing, shipping routes, or batch availability before committing.

How 4‑MeTMP threo‑4‑Methylmethylphenidate fits into wider NPS research

Academic and forensic reports on newer phenidate‑based NPS describe a growing list of analogues sold to researchers and later detected in casework. According to monographs from specialist NPS groups and open‑access toxicology publications, 4‑MeTMP appears in that same pipeline; originally characterised for transporter binding, then re‑emerging in the research chemical space for method development.

Where toxicological modelling has been performed on closely related ring‑substituted phenidates, predictions point toward non‑trivial acute toxicity, cardiotoxic potential related to hERG channel interactions, and possible respiratory and gastrointestinal concerns, even without established clinical dosing references. This is one of the reasons we stress that 4‑MeTMP is not for human consumption and belongs in controlled, well‑documented experiments only.

For labs already working with novel opioids such as buy etonitazene online, buy isotonitazene online, buy protonitazene online, or benzodiazepine analogues like rilmazafone, adding 4‑MeTMP creates a broader internal library that reflects what forensic and clinical toxicology labs encounter in the wild.

Table 2: 4‑MeTMP and Related Davechemicals.com Research Products

All items are sold for research use only and must not be used for human or veterinary applications.

Legal and safety context of 4‑MeTMP in key regions

While specific scheduling of 4‑MeTMP itself can vary or remain undefined, regulators in the UK, US, Germany, Australia, and parts of Asia have steadily tightened frameworks around novel psychoactive substances and analogues of controlled medicines.

According to the UK Temporary Class Drug notice referenced on Wikipedia’s 4‑Methylmethylphenidate page, 4‑MeTMP was previously covered due to unapproved sale as a designer drug in that market. In the United States, the combination of methylphenidate’s Schedule II status and the federal analogue act means structurally related compounds, if intended for human use, may fall under enforcement even if not explicitly named.

Researchers in jurisdictions like Germany and Australia are already familiar with NPS legislation that controls entire classes instead of listing each substance individually, particularly for stimulants and synthetic cannabinoids. Because of this, we strongly advise that every lab consult its local regulations and internal compliance officers before buying 4‑MeTMP online, or any other specialised item such as 4F‑ADB, AM‑2201, SGT‑25, or buy 5F‑UR‑144 online.

Table 3: Key Takeaways for 4‑MeTMP threo‑4‑Methylmethylphenidate Research

FAQs: 4‑MeTMP threo‑4‑Methylmethylphenidate Research ❓

1. What is 4‑MeTMP threo‑4‑Methylmethylphenidate used for in research?

4‑MeTMP is mainly used in preclinical and analytical studies that examine dopamine and noradrenaline transporter interactions, and in NPS and forensic reference libraries. It helps map how subtle structural changes alter binding affinity and functional reuptake inhibition compared with classical methylphenidate.

2. Is 4‑MeTMP legal to order for my lab?

The legal status of 4‑MeTMP is jurisdiction-specific, and in some countries, it may be controlled by analogue or NPS legislation even when not listed by name. Laboratories in the UK, US, Germany, Australia, and Asia should consult local schedules and internal legal teams before ordering.

3. Is 4‑MeTMP threo‑4‑Methylmethylphenidate safe?

There is no established clinical safety profile for 4‑MeTMP, and related modeling work for ring-substituted phenidates indicates non-trivial acute toxicity and cardiotoxic risk. This is why we sell it strictly for research use, not for human or veterinary applications.

4. How does 4‑MeTMP differ from methylphenidate?

Structural differences are subtle, but 4‑MeTMP has a 4‑methyl group on the phenyl ring and shows lower efficacy as a functional dopamine reuptake inhibitor while retaining high binding at the transporter. Methylphenidate, by contrast, is an established medicine with well defined pharmacokinetics and clinical indications.

5. Where can researchers buy 4‑MeTMP threo‑4‑Methylmethylphenidate online?

Researchers can obtain 4‑MeTMP from specialist suppliers, including Davechemicals.com and analytical companies like Cayman Chemical. Orders should always be placed by authorised personnel within licensed institutions.

Key Takeaways for Labs 🧪

• 4‑MeTMP threo‑4‑Methylmethylphenidate is a phenidate analogue with high dopamine transporter affinity but lower functional reuptake efficacy than methylphenidate, making it a sharp tool for transporter research.
• There is no approved medical use, and toxicological modelling on related substances signals meaningful risk, so this compound belongs in controlled research settings only.
• Davechemicals.com offers 4‑MeTMP alongside other tightly focused research stimulants, dissociatives, opioids, and synthetic cannabinoids, including buy methylone online, buy eutylone online, buy 5F‑MDMB‑2201 online, and adbb powder, all clearly labelled for non‑human use.

If your lab is ready to integrate 4‑MeTMP threo‑4‑Methylmethylphenidate into its research portfolio, you can review current availability or contact our team directly via Davechemicals.com Contact.

1 2 3  5 6 7 8 9 10