Buy 5F-UR144 online (XLR-11)
At Davechemicals.com, we take pride in offering compounds like 5F-UR-144 (XLR-11) that fuel groundbreaking research. This synthetic cannabinoid has intrigued scientists since its emergence, blending potent activity with a unique chemical profile. We crafted this guide to illuminate its facets, drawing from credible sources to ensure accuracy and depth. Whether you seek to understand its origins or explore applications, we cover it all. For those ready to incorporate it into studies, check out our 5F-UR-144
Evidence points to 5F-UR-144 as a compound with significant affinity for cannabinoid receptors, yet questions linger about its full implications. Research suggests it mimics some cannabis effects, but with added potency due to fluorination. It seems likely that its use in blends has led to varied outcomes, highlighting the need for caution in experiments.
Key Points:
- 5F-UR-144 acts as a full agonist at CB1 and CB2 receptors, potentially more effective than some analogs.
- Legality varies; it’s controlled in many regions, including the UK and US.
- Associated risks include kidney issues, though evidence leans toward rare occurrences in controlled settings.
- For research, purity matters; we ensure top standards at Davechemicals.com.
Understanding the Basics of Synthetic Cannabinoids
Synthetic cannabinoids like XLR-11 represent a class of lab-created molecules designed to interact with the body’s endocannabinoid system. Unlike natural cannabis, these compounds offer precise control in studies. At Davechemicals.com, we stock a range including buy ADB-FUBINACA online and buy JWH-122 online, all for scientific use.
PRODUCT SPECIFICATION
- Product Name: 5F-UR144
- IUPAC Name: (1-(5-fluoropentyl)-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone
- Other Names: XLR11, FUB144
- Cas Number: 1364933-54-9
- Molecular Formula: C21H28FNO
- Appearance: Crystal and powder
- Application: Research purposes
The Chemical Makeup Revealed
The structure of 5F-UR-144 includes an indole core linked to a tetramethylcyclopropyl group and a fluoropentyl chain. This design enhances its binding strength. According to PubChem, its formula is C21H28FNO, with a molar mass of 329.459 g/mol.
Potential Applications in Research
Scientists value XLR-11 for probing receptor dynamics. Studies indicate it induces hypothermic responses in models, useful for understanding thermoregulation.
At Davechemicals.com, we delve deeply into compounds like 5F-UR-144 (XLR-11), providing not just products but knowledge to empower your work. This extensive overview draws from peer-reviewed sources, offering a comprehensive look at this synthetic cannabinoid. We emphasize its role in research while acknowledging debates around its profile.
🔍 What Is 5F-UR-144 Exactly?
5F-UR-144, or XLR-11, emerges as a fluorinated derivative of UR-144, a compound initially explored for pharmaceutical potential. Identified in 2012 within herbal mixtures, it quickly gained attention for its cannabinoid-mimicking properties. As detailed on Wikipedia, it features a 1-(5-fluoropentyl)-1H-indol-3-yl group attached to a (2,2,3,3-tetramethylcyclopropyl)methanone. This structure sets it apart from classics like JWH-018, which we also offer.
Boldly, 5F-UR-144 binds to CB1 and CB2 receptors with EC50 values of 98 nM and 83 nM, respectively. Such potency makes it a staple in binding assays. Researchers in the United Kingdom, United States, Germany, Australia, and Asia turn to it for insights into neuropharmacology.
History of XLR-11: From Lab to Spotlight
The story of XLR-11 begins in grey-market innovation. Unlike patented compounds from Abbott Laboratories, it surfaced independently for recreational blends. By 2012, detections in products like spice led to scrutiny. A DEA report highlights its placement in Schedule I, reflecting concerns over misuse.
In our experience at Davechemicals.com, demand spiked as labs sought analogs post-bans on earlier ones like AM-2201. This evolution underscores the dynamic field of research chemicals.
📊 Table 1: Chemical Properties of 5F-UR-144 Compared to Analogs
| Compound | Formula | Molar Mass (g/mol) | CB1 EC50 (nM) | CB2 EC50 (nM) |
|---|---|---|---|---|
| 5F-UR-144 (XLR-11) | C21H28FNO | 329.459 | 98 | 83 |
| UR-144 | C21H29NO | 311.468 | 150 | 118 |
| JWH-018 | C24H23NO | 341.451 | 9 | 2.94 |
| AM-2201 | C24H22FNO | 359.442 | 1 | 2.6 |
| 5F-ADB | C20H27FN2O3 | 362.444 | 0.59 | 2.7 |
Data sourced from peer-reviewed studies; values approximate based on available literature.
Fluorination in 5F-UR-144 boosts metabolic stability, a trait shared with 4F-ADB.
Pharmacology: How Does XLR-11 Work?
As a cannabinoid receptor agonist, XLR-11 activates pathways similar to THC. A study in ACS Chemical Neuroscience shows it triggers hypothermia in rats at 3 mg/kg, indicating strong CB1 activity. In human terms, this translates to potential stimulant-like responses, though no hallucinogens were noted in analogs like UR-144 per MDPI Biology.
We recommend pairing it with tools like buying 5F-MDMB-2201 online for comparative assays.
Subjective Effects and Duration: What Researchers Observe
While human data is limited, analogs suggest 5F-UR-144 induces euphoria, increased heart rate, and appetite. Duration spans 1-4 hours when smoked, based on UR-144 studies. Peak effects hit within 20 minutes.
“Synthetic cannabinoids like XLR-11 produce cardiovascular changes comparable to THC, but with varying intensity,” notes a report in Biology.
Explore our blog on what are synthetic cannabinoids.
Risks and Toxicity: The Unvarnished Truth
Evidence leans toward associations with acute kidney injury (AKI), as per CDC reports. Fatalities linked solely to XLR-11 appear in Forensic Science International, with blood levels at 1.4 ng/mL. Genotoxicity shows in comet assays, per PMC.
We stress: For research only. Avoid assumptions; verify through experiments.
📊 Table 2: Legal Status of 5F-UR-144 Across Key Regions
| Country/Region | Status | Effective Date | Notes |
|---|---|---|---|
| United States | Schedule I | January 2024 | DEA controlled; research permits required. |
| United Kingdom | Class B | 2016 | Under the Misuse of Drugs Act. |
| Germany | Anlage II | 2016 | Trade authorised, not prescribable. |
| Australia | Schedule 9 | 2013 | Prohibited except for research. |
| China (Asia example) | Controlled | October 2015 | Banned for non-medical use. |
| Brazil | Class F2 | July 2023 | Prohibited psychotropics. |
| New Zealand | Temporary Class | July 2012 | Banned sales. |
Compiled from official sources; check local laws for updates.
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Best Practices for Handling XLR-11 in Labs
Store in cool, dry conditions. Use gloves, as fluorinated compounds demand care. For assays, dilute carefully.
Image Suggestion: Visualizing the Molecule
Insert a 3D model of XLR-11 here. Caption: “Molecular structure of 5F-UR-144, highlighting the fluoropentyl chain (source: PubChem).”
How to Use 5F-UR-144 in Studies
In vitro, test receptor binding; in vivo, monitor physiological changes. Pair with buy ADB-BUTINACA online.
Where Can Researchers Source Quality Samples?
Look no further than our shop. We ship discreetly worldwide.
When Was XLR-11 First Discovered?
Around 2012, as per forensic data.
Why Is 5F-UR-144 Controversial?
Due to misuse of links, yet valuable in science.
Which Analogs Complement XLR-11 Research?
Consider buy SGT-25 online or buy 5F-MDA-19.
Buy 5F-UR-144 in the United Kingdom for Neuroscience Studies
UK researchers, our stock complies with regs. Explore buy research chemicals UK. Similar for US, Germany, Australia, Asia.
📊 Table 3: Potential Effects and Risks Matrix
| Category | Positive/Neutral Effects | Potential Risks | Study References |
|---|---|---|---|
| Physiological | Increased HR, BP | AKI, hypothermia | CDC, ACS Chem Neurosci |
| Subjective | Euphoria, stimulation | Anxiety, paranoia | MDPI Biology |
| Toxicological | N/A | Genotoxicity, fatalities | PMC, Forensic Sci Int |
| Duration | 1-4 hours | Prolonged in high doses | Analog data |
| Research Value | Receptor studies | Legal hurdles | DEA |
Based on compiled research, consult primary sources.
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Frequently Asked Questions
- What is 5F-UR-144 used for in research?
It serves in studying cannabinoid receptor agonists, aiding neuroscience. - Is XLR-11 legal in the United States?
No, it’s Schedule I since 2024. - What are the effects of 5F-UR-144?
Similar to cannabis, with stimulant notes, per analogue studies. - How to buy 5F-UR-144 online safely?
Choose reputable sites like Davechemicals.com for lab-grade. - What risks come with XLR-11?
Potential AKI and toxicity, as reported in cases.
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