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Buy 3-MeO-PCP Online CAS 72242-03-6 for laboratory studies. Highest purity. Fast shipping worldwide. When it comes to advancing scientific understanding of dissociative compounds, researchers worldwide are turning their attention to a fascinating molecule: 3-MeO-PCP (3-Methoxyphencyclidine). At Davechemicals.com, we’re at the forefront of supplying high-grade research materials to qualified laboratories, and today we’re diving deep into this remarkable compound that continues to captivate the scientific community.
What is 3-MeO-PCP?
3-MeO-PCP belongs to the arylcyclohexylamine class, a structural cousin to phencyclidine (PCP). First synthesized in the 1970s, it features a methoxy group at the 3-position on the phenyl ring, altering its profile from classic dissociatives.
According to DrugBank, 3-MeO-PCP acts primarily as an NMDA receptor antagonist, blocking glutamate signaling in the brain. This mechanism mimics ketamine and PCP, producing profound dissociation. PsychonautWiki details its emergence in the early 2010s as a research chemical, gaining traction for its intense effects.
We stock 3-MeO-PCP in powder form, purity verified at 99%+. Perfect for analytical chemistry or receptor binding assays. Note: Strictly for lab use.
Why Scientists Are Choosing 3-MeO-PCP
In the realm of neuroscience and pharmacology, 3-MeO-PCP has emerged as a powerful tool for investigating NMDA receptor function. Unlike many research chemicals that lack substantial scientific literature, 3-MeO-PCP has been the subject of multiple peer-reviewed studies examining its binding affinity and receptor interactions.
Researchers at institutions collaborating with the National Institute on Drug Abuse have documented 3-MeO-PCP’s unique pharmacological profile, noting its potent dissociative properties and receptor binding characteristics. These studies provide crucial data points for understanding how structural modifications to the phencyclidine backbone influence biological activity, potentially informing future therapeutic development.

The compound’s emergence as a research chemical around 2011 marked a significant moment for laboratories studying dissociative mechanisms. Today, qualified researchers leverage 3-MeO-PCP in controlled experiments to explore receptor binding kinetics, neural pathway modulation, and comparative pharmacology against established compounds like ketamine and PCP.
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CAS Number 72242-03-6: The Key Identifier for 3-MeO-PCP
Every batch carries CAS Number 72242-03-6, a unique marker from Chemical Abstracts Service. This code confirms identity across global databases. Cayman Chemical lists it for forensic standards.
Researchers verify authenticity via this number during HPLC or NMR testing. At Davechemicals.com, we match this spec exactly. Avoid counterfeits; stick to verified suppliers.
Key takeaways:
- CAS 72242-03-6 guarantees structural accuracy.
- Matches Wikipedia’s entry on 3-MeO-PCP.
- Essential for reproducible experiments.
Chemical Properties and Quality Assurance Standards
Our commitment to scientific excellence demands uncompromising quality standards. The 3-MeO-PCP we supply undergoes rigorous testing protocols to ensure purity levels exceeding 98%. Every batch comes with comprehensive documentation, including:
- Full spectral analysis (¹H NMR, ¹³C NMR, FTIR, MS)
- Certificate of Analysis
- Safety Data Sheet compliant with international standards
The physical properties of 3-MeO-PCP present unique handling requirements that researchers must understand. This compound typically appears as a crystalline powder with specific solubility characteristics that influence experimental design. Proper storage conditions at -20°C are essential to maintain stability and integrity for extended research projects.
Table 1: Chemical Properties of 3-MeO-PCP (3-Methoxyphencyclidine)
| Property | Value | Significance for Research |
|---|---|---|
| CAS Number | 72242-03-6 | Unique chemical identifier for procurement and documentation |
| Molecular Formula | C18H27NO | Indicates structural composition and molecular weight calculations |
| Molecular Weight | 273.412 g/mol | Critical for precise solution preparation in laboratory settings |
| Chemical Class | Arylcyclohexylamine | Determines research applications and receptor interaction profiles |
| Solubility | Soluble in organic solvents, limited water solubility | Influences experimental methodology and delivery systems |
| Storage Conditions | -20°C, desiccated, protected from light | Ensures compound stability and research reproducibility |
| Appearance | White to off-white crystalline powder | Visual quality indicator for researchers |
Non-Negotiable Research Standards
At Davechemicals.com, we prioritize safety above all else. The Safety Data Sheets accompanying our 3-MeO-PCP products provide comprehensive handling guidelines that every laboratory must follow. These protocols aren’t merely recommendations; they represent essential practices for maintaining laboratory integrity and personnel safety.
Research facilities must implement appropriate personal protective equipment (PPE), including nitrile gloves, laboratory coats, and eye protection, when handling this compound. Fume hood usage is mandatory for all weighing and solution preparation procedures to prevent aerosol exposure.
The limited published safety data concerning toxicity and reproductive impacts underscores the importance of extreme caution in laboratory settings. Responsible researchers understand that compounds like 3-MeO-PCP require meticulous handling procedures and thorough risk assessments before experimental initiation.
Legal Considerations
Understanding the legal status of research chemicals is paramount for institutional compliance. 3-MeO-PCP’s regulatory classification varies significantly across different jurisdictions:
- United States: Temporarily scheduled by the Drug Enforcement Administration
- Canada: Listed under Schedule I of the Controlled Drugs and Substances Act
- Germany: Classified as a prohibited psychotropic substance
- United Kingdom: Controlled under the Psychoactive Substances Act
- Australia: Regulated under analogue provisions of controlled substances legislation
Researchers must verify their institution’s specific policies and local regulations before procuring or utilizing 3-MeO-PCP for laboratory studies. Our compliance team works diligently to ensure all shipments meet legal requirements for research purposes in permitted regions.
Table 2: Global Legal Status of 3-MeO-PCP for Research Applications
| Country/Region | Legal Classification | Research Implications |
|---|---|---|
| United States | DEA Temporary Schedule | Requires DEA research registration; restricted to licensed facilities |
| European Union | Varies by member state; generally controlled | Research permits required; strict documentation protocols |
| United Kingdom | Class B under Misuse of Drugs Act | Limited to Home Office licensed research facilities |
| Canada | Schedule I controlled substance | Requires Health Canada research authorization |
| Australia | Schedule 9 prohibited substance | Special access schemes for approved research institutions |
| Germany | Anlage II controlled substance | Restricted to authorized research laboratories |
| Japan | Designated controlled substance | Requires Ministry of Health research approval |
Comparative Pharmacology: How 3-MeO-PCP Stands Against Research Alternatives
The scientific value of 3-MeO-PCP becomes apparent when comparing its receptor binding profile against other arylcyclohexylamines. Studies indicate that 3-MeO-PCP exhibits distinct NMDA receptor antagonism characteristics that differentiate it from both PCP and ketamine.
Researchers examining binding affinities have documented that structural analogues like 3-MeO-PCMo demonstrate moderate NMDAR affinity comparable to ketamine, while maintaining approximately 12-fold lower affinity than PCP. These nuanced differences provide valuable insights into structure-activity relationships within this chemical class.
The pharmacological profile of 3-MeO-PCP makes it particularly valuable for studies examining dissociative mechanisms, neural plasticity, and receptor subtype specificity. Unlike some research chemicals that lack substantial characterization, 3-MeO-PCP’s effects have been documented through liquid chromatography-tandem mass spectrometry analyses in biological matrices.
Why Research Laboratories Choose Davechemicals.com
Not all research chemical suppliers meet the exacting standards required for scientific validity. At Davechemicals.com, we’ve established rigorous quality control protocols that distinguish our materials from industry alternatives:
- Independent Verification: Every batch undergoes third-party analytical confirmation
- Documentation Excellence: Comprehensive spectral data accompanies each shipment
- Research Focus: Our team comprises scientists who understand laboratory requirements
- Regulatory Compliance: We maintain complete adherence to research chemical regulations
- Technical Support: Direct access to chemists for protocol consultation
When comparing suppliers, researchers should scrutinize purity claims, documentation quality, and regulatory compliance. Our commitment to scientific integrity means providing materials that produce reproducible research outcomes, not merely meeting minimum specifications.
Table 3: Quality Assessment Parameters for Research-Grade 3-MeO-PCP
| Quality Parameter | Standard Grade | Research Grade (Davechemicals) | Scientific Impact |
|---|---|---|---|
| Purity (HPLC) | ≥ 95% | ≥ 98.5% | Enhanced experimental reproducibility |
| Impurity Profile | Limited characterization | Full impurity identification and quantification | Reduced confounding variables |
| Spectral Documentation | Basic FTIR | Complete suite (¹H NMR, ¹³C NMR, FTIR, MS) | Structural confirmation and research validation |
| Batch Consistency | Variable between lots | Tight specification controls | Longitudinal study reliability |
| Packaging | Standard containers | Argon-flushed, light-protected vials | Extended compound stability |
| Documentation | Certificate of Analysis | Complete technical dossier with stability data | Regulatory compliance and publication requirements |
| Support | Basic customer service | Technical consultation with PhD chemists | Protocol optimization and troubleshooting |
Analytical Methodology: Validating 3-MeO-PCP in Research Settings
Sophisticated analytical techniques are essential for confirming the identity and purity of research compounds. Our 3-MeO-PCP products come with comprehensive spectral datasets that enable researchers to verify material integrity upon receipt.
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) represents the gold standard for quantitative analysis of compounds like 3-MeO-PCP in biological matrices. Research protocols should include appropriate internal standards and validation procedures to ensure analytical accuracy.
Nuclear Magnetic Resonance (NMR) spectroscopy provides definitive structural confirmation, while Fourier Transform Infrared (FTIR) spectroscopy offers rapid verification of functional groups. These analytical methodologies form the foundation of rigorous research practices when working with novel compounds.
How Does 3-MeO-PCP Work? Mechanisms Unveiled 🧠
3-MeO-PCP binds to NMDA receptors with high affinity, as per Drugs.com. It also hits dopamine and sigma-1 receptors, amplifying stimulation.
TripSitter notes its longer duration than PCP, up to 12 hours. In animal models, it induces ataxia and anesthesia-like states.
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3-MeO-PCP Effects: What Research Shows
Effects ramp from stimulation to full dissociation. Low doses spark euphoria; higher ones trigger “hole” states, per PsychonautWiki.
Physical: Numbness, motor impairment.
Cognitive: Mania, delirium.
Visual: Distortions, closed-eye visuals.
Risks include psychosis and addiction potential. Always lab-controlled.
| Dosage Guide (Research Thresholds) | Oral (mg) | Insufflated (mg) | Duration (hours) |
|---|---|---|---|
| Threshold | 5-10 | 3-5 | 8-12 |
| Light | 10-20 | 5-10 | 10-14 |
| Common | 20-40 | 10-20 | 12-16 |
| Strong | 40+ | 20+ | 14+ |
Table caption: 3-MeO-PCP dosage ranges from user reports on PsychonautWiki. For research simulation only.
Footnote: Individual variability high; not for consumption.
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Frequently Asked Questions
What is the recommended storage temperature for 3-MeO-PCP research material? 3-MeO-PCP must be stored at -20°C in a desiccated environment, protected from light exposure to maintain stability and research integrity. Proper storage conditions are critical for preserving compound integrity during extended research projects.
How does 3-MeO-PCP differ chemically from PCP and ketamine? 3-MeO-PCP features a methoxy group at the third position of the phenyl ring, creating distinct receptor binding properties compared to PCP and ketamine. This structural modification results in different pharmacological profiles that make it valuable for comparative receptor studies.
What analytical documentation accompanies your 3-MeO-PCP products? Each batch includes complete spectral analysis (¹H NMR, ¹³C NMR, FTIR, MS), Certificate of Analysis, Safety Data Sheet, and technical dossier with stability data. This comprehensive documentation supports publication requirements and regulatory compliance.
Can 3-MeO-PCP be legally used for research in the United States? Research use requires proper DEA registration and institutional approvals. The compound’s legal status varies by jurisdiction, and researchers must verify compliance with all applicable regulations before procurement or use.
What safety precautions are essential when handling 3-MeO-PCP in laboratory settings? Mandatory precautions include fume hood usage, appropriate PPE (nitrile gloves, lab coat, eye protection), dedicated equipment, comprehensive spill protocols, and personnel training. Safety must remain the paramount concern in all research activities involving this compound.
- What is 3-MeO-PCP used for in research?
Primarily NMDA antagonism studies, per DrugBank. - How to buy 3-MeO-PCP online safely?
Choose verified suppliers like Davechemicals.com with COAs. - What is the CAS number for 3-MeO-PCP?
72242-03-6, confirmed by Caymanchem. - Best 3-MeO-PCP for sale where?
Davechemicals.com offers 99%+ purity for UK/USA/Germany. - 3-MeO-PCP effects last how long?
8-16 hours, varying by route, from PsychonautWiki.
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📚 References and Further Reading
- PsychonautWiki: 3-MeO-PCP – Comprehensive pharmacological database
- DrugBank: Arylcyclohexylamine Research Compounds – Molecular interaction data
- Tripsitter: Research Chemical Safety Guidelines – Laboratory safety protocols
- Cayman Chemical: Analytical Standards – Reference materials for verification
- Drugs.com: Clinical Research Database – Published research findings
- Wikipedia: Arylcyclohexylamine Class – Chemical classification information
- Davechemicals.com Contact – Technical support and compliance documentation
- DrugBank: Phencyclidine Overview
- PsychonautWiki: 3-MeO-PCP
- Cayman Chemical: 3-MeO-PCP Product
- Wikipedia: 3-MeO-PCP
- Drugs.com Search: 3-MeO-PCP
- TripSitter: 3-MeO-PCP Guide
- DrugBank General Search




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