Buy 2-CMC (2-Chloromethcathinone) Online – High Purity Stimulant Research Chemical.
Looking to buy 2-CMC online for research purposes? 2-Chloromethcathinone (2-CMC) is a popular stimulant research chemical belonging to the cathinone class. Known for its focus-enhancing and energy-boosting properties, 2-CMC has become increasingly sought after in laboratories around the globe. 2‑CMC (2‑chloromethcathinone) is a synthetic stimulant from the cathinone family, structurally related to methcathinone and often sold as a research chemical, with significant safety and legal risks in many countries.
What is 2‑CMC (2‑Chloromethcathinone) and why are researchers interested?
2‑CMC (2‑Chloromethcathinone) is a synthetic stimulant from the cathinone class, structurally related to the naturally occurring stimulant cathinone found in Catha edulis (khat). It is often encountered as a hydrochloride salt, which improves stability and solubility for analytical work in laboratory settings.
Chemically, 2‑CMC is described as 1‑(2‑chlorophenyl)‑2‑(methylamino)propan‑1‑one, placing it in the same broad family as methcathinone and mephedrone, which interact with monoamine transporters in the brain. According to data from forensic laboratories, chloromethcathinone isomers can act as stimulants at dopamine, serotonin and norepinephrine transporters, which explains their interest to toxicologists and forensic scientists.
How does 2‑CMC fit into the synthetic cathinone family?
Synthetic cathinones form a large group of new psychoactive substances structurally related to cathinone, with many entries described in resources such as DrugBank and Drugs.com. 2‑CMC belongs to the chloromethcathinone subgroup, which includes 2‑, 3‑ and 4‑chloromethcathinone isomers, each having different substitution patterns on the phenyl ring.
Analytical reports indicate that chloromethcathinone isomers show stimulant activity similar to methyl‑substituted cathinones like mephedrone (4‑MMC), making them relevant in toxicology and forensic casework. On sites such as PsychonautWiki and TripSitter, synthetic cathinones are often described in terms of onset, duration and subjective profiles, though these descriptions are anecdotal and not a replacement for controlled scientific data.
Our lab‑grade positioning at Davechemicals.com
At Davechemicals.com official website, we present 2‑CMC exclusively as a laboratory research material, not for human consumption, veterinary use or any form of personal use. We work with vetted partners who require standards for chromatography, spectroscopy and method development, particularly when building analytical libraries alongside other materials such as 3‑MMC, 2‑FDCK or methylone.
Our catalogue includes a wide range of stimulant, dissociative and cannabinoid research materials, including 4‑METMP, 4‑MPD, NEP, 3‑MeO‑PCP and 5‑MeO‑DMT, to support comparative analytical work. This structure allows laboratories across the UK, USA, Germany, Australia and Asia to order multiple standards from one trusted source, subject to legal checks.[3]
Chemical profile of 2‑CMC (2‑Chloromethcathinone)
According to analytical monographs, 2‑CMC is typically identified as a white or off‑white solid, with a molecular formula of C10H12ClNO and a molecular weight close to 197.7. It is often present as the hydrochloride salt, which allows easier dissolution in polar solvents used in lab workflows.
Experimental work indicates that chloromethcathinone isomers act as monoamine transporter ligands at dopamine, serotonin and norepinephrine transporters, with activity comparable to some methyl‑substituted cathinones that have been used recreationally. These observations align with broader patterns described in reference resources such as DrugBank and Cayman Chemical, which document how small structural changes in cathinones can influence potency, selectivity and toxicity.
Researchers working on stimulant pharmacology often explore how 2-CMC affects mental and physical performance.
| Property | Details |
|---|---|
| Product Name | 2-CMC |
| Synonyms | 2-Chloromethcathinone, 2-CMC HCL |
| IUPAC Name | 1-(2-chlorophenyl)-2-(methylamino)-1-propanone |
| 1-(2-chlorophenyl)-2-(methylamino)propan-1-one | |
| CAS Number | 90869-66-2, 692720-34-6 |
| Molecular Formula | C₁₀H₁₂ClNO • HCl |
| Molar Mass | 197.66 g/mol |
| InChI Code | InChI=1S/C10H12ClNO.ClH/c1-7(12-2)10(13)8-5-3-4-6-9(8)11;/h3-7,12H,1-2H3;1H |
| InChI Key | RMOPJSWYMQGLJP-UHFFFAOYSA-N |
| SMILES | O=C(C(NC)C)C1=C(Cl)C=CC=C1.Cl |
| Solubility | DMF: 1 mg/ml |
| DMSO: 5 mg/ml | |
| Ethanol: 1 mg/ml | |
| PBS (pH 7.2): 10 mg/ml | |
| Formulation | A crystalline solid |
| Purity | ≥99% |
Chemical Structure and Properties
2-CMC has the chemical formula C10H12ClNO and a molecular weight of 197.66 g/mol. It exists as two enantiomers: (R)-2-chloromethcathinone and (S)-2-chloromethcathinone. The structure of 2-CMC is similar to other cathinone derivatives, with a chlorine atom attached to the phenyl ring.
Table 1: 2‑CMC basic research profile
Table 1. Core laboratory information for 2‑CMC (2‑Chloromethcathinone)
| Parameter | Detail |
|---|---|
| Chemical class | Synthetic cathinone stimulant |
| IUPAC name | 1‑(2‑chlorophenyl)‑2‑(methylamino)propan‑1‑one |
| Typical form | Hydrochloride salt, crystalline solid |
| Molecular formula | C10H12ClNO |
| Reported action | Stimulant activity at monoamine transporters |
| Primary use in labs | Analytical reference standard, method development and forensic toxicology |
| Availability on Davechemicals.com | Research‑use only, subject to local regulations |
Note: All information above refers to research and analytical use, not clinical or therapeutic use.
Legal status of 2‑CMC in the UK, USA, Germany, Australia and Asia
Synthetic cathinones have been widely targeted by controlled substance legislation, but specific scheduling of 2‑CMC varies between regions and sometimes falls under analogue or blanket NPS laws. Many countries regulate substances that are structurally related to listed cathinones, which can bring 2‑CMC under control even when it is not explicitly named.
Regulatory frameworks in Europe, North America and Australia increasingly use generic definitions for substituted cathinones, which may cover 2‑chloromethcathinone and related analogues. According to a recent focus from forensic institutes and monitoring bodies, chloromethcathinone isomers have been detected in casework, which tends to accelerate scheduling discussions. Anyone working with 2‑CMC must review current local law and seek formal legal advice, since the status can change quickly.
How laboratories typically handle 2‑CMC safely
Forensic and toxicology laboratories that study 2‑CMC usually apply the same safety culture used for other stimulant research chemicals, for example, those described on TripSitter and PsychonautWiki for informational purposes. This includes controlled access, accurate labelling, protective equipment and documented disposal protocols.
Analytical work with 2‑CMC often involves LC‑MS, GC‑MS or NMR to confirm identity, again similar to workflows used for substances like etonitazene, 5F‑UR‑144 or AM‑2201 when setting up spectral libraries. Structures and reference spectra are often cross‑checked against databases and reference suppliers such as Cayman Chemical.
Table 2: 2‑CMC vs other popular research stimulants
Table 2. Comparison of 2‑CMC with selected stimulant research chemicals
| Research material | Broad class | Notable feature in the research context | Related products on Davechemicals.com |
|---|---|---|---|
| 2‑CMC (2‑Chloromethcathinone) | Synthetic cathinone | Chlorinated cathinone, monoamine transporter activity | 2‑CMC product page on Davechemicals.com |
| NEP | Synthetic cathinone | Frequently used as a comparator in cathinone panels | Buy NEP online |
| 4‑MPD | Piperidine stimulant | Used in some labs as a model dopamine reuptake inhibitor | Buy 4‑MPD online |
| 4‑METMP | Methylphenidate analogue | Structurally related to methylphenidate, studied for transporter binding | Buy 4‑METMP |
| Methylone | Synthetic cathinone | MDMA‑like structure, reference material in many forensic labs | Buy methylone online |
Note: All substances above are research chemicals, not approved medications, and are supplied strictly for laboratory use.
Where can qualified buyers buy 2‑CMC for research purposes? 🧪
For vetted institutions looking to buy 2‑CMC research material, Davechemicals.com’s official website lists 2‑CMC among its synthetic cathinone range, with tiered pricing for gram to bulk orders, subject to compliance checks. Our ordering process checks the destination country, intended use and regulatory environment before any shipment is prepared.
Laboratories that already work with dissociatives such as 2‑FDCK, N‑ethyl ketamine or deoxymethoxetamine, or with benzodiazepine standards like diclazepam and alprazolam powder, can streamline logistics by sourcing multiple compounds from one supplier. This approach reduces administrative overhead but never bypasses the requirement to comply with local law.
Why 2‑CMC attracts attention in UK, USA, Germany, Australia and Asia
Law enforcement and toxicology reports in Europe and North America have documented chloromethcathinone isomers in seized materials and biological specimens, suggesting that these substances circulate in some markets as NPS stimulants. This presence makes 2‑CMC relevant for analytical reference libraries in the UK, USA and Germany, where forensic laboratories need to identify many similar analogues quickly.
For Australia and parts of Asia, generic cathinone bans and customs controls mean that any appearance of 2‑CMC requires rapid analytical confirmation and clear documentation. Research materials such as 2‑CMC, 3‑MMC or 4‑FA therefore serve a technical role in test development, not a consumer role.
Key takeaways for researchers considering 2‑CMC
- 2‑CMC (2‑Chloromethcathinone) is a synthetic cathinone stimulant structurally related to methcathinone and mephedrone.
- It interacts with dopamine, serotonin and norepinephrine transporters, making it important for monoamine transporter research and forensic toxicology.
- Legal status is highly jurisdiction‑dependent, often covered by analogue or blanket cathinone laws in Europe, North America and Australia.
- Davechemicals.com supplies 2‑CMC as a research chemical only, alongside standards such as NEP, methylone and 3‑MMC, following strict compliance checks.
- No therapeutic use is approved, and any non‑laboratory use carries significant safety and legal risks.
Table 3: Example Davechemicals.com research portfolio around 2‑CMC
Table 3. Selected Davechemicals.com research products related to stimulant, dissociative and psychedelic work
| Category | Example product | Typical lab use (research context) |
|---|---|---|
| Synthetic cathinones | Buy 3‑MMC | Comparative analysis with 2‑CMC in stimulant panels |
| Dissociatives | Buy 2‑FDCK online | Development of LC‑MS methods for arylcyclohexylamines |
| Classic‑type chems | Buy mescaline powder | Reference spectra and cross‑reactivity checks |
| Tryptamines | 5‑MeO‑DMT | Psychedelic panel development and qualitative analysis |
| Benzodiazepines | Diclazepam | Forensic benzodiazepine screening calibration |
| Synthetic cannabinoids | AM‑2201 | Expansion of synthetic cannabinoid detection libraries |
Note: Product availability, legal status and allowable uses differ by country and change over time. Buyers must verify current regulations before ordering.
FAQs: What is 2‑CMC (2‑Chloromethcathinone)?
What is 2‑CMC (2‑Chloromethcathinone) in simple terms?
2‑CMC is a synthetic stimulant belonging to the cathinone family, structurally similar to methcathinone and related NPS stimulants. It is researched mainly as a reference material for forensic and toxicology laboratories, not as a medicine.
Is 2‑CMC the same as other chloromethcathinones like 3‑CMC or 4‑CMC?
No. Chloromethcathinone exists as 2‑, 3‑ and 4‑isomers, which differ in where the chlorine sits on the phenyl ring. These structural differences can affect potency, receptor binding and risk profile, so each is treated as a distinct compound in scientific work.
Is 2‑CMC legal in the UK, USA, Germany, Australia or Asia?
Legal status differs between countries and can change. Many jurisdictions use analogue or generic cathinone laws that may cover 2‑CMC even if it is not explicitly named. Anyone considering work with 2‑CMC must check current local legislation and obtain legal advice, and this answer is not legal guidance.
Does 2‑CMC have any approved medical uses?
There is no recognised therapeutic approval for 2‑CMC in major regulatory databases such as DrugBank or in prescribing resources like Drugs.com. Research has focused on analytical characterisation and toxicology, rather than clinical development.
How do labs usually obtain 2‑CMC safely for research?
Labs typically purchase 2‑CMC from vetted research chemical suppliers such as Davechemicals.com official website, or from specialist reference providers, and require appropriate institutional approval before ordering. Orders are limited to research use, packaged securely and accompanied by documentation for identification and compliance.
How does 2‑CMC compare to substances like methylone or 3‑MMC?
Methylone and 3‑MMC are also synthetic cathinones, but they differ structurally and have been more widely documented in toxicology and case reports. 2‑CMC shares the broad stimulant profile yet remains less characterised, which is why analytical reference work is still ongoing.
Are there known risks or toxicity concerns with 2‑CMC?
Monoamine transporter stimulants such as chloromethcathinone isomers raise concerns about cardiovascular strain, neurotoxicity and behavioural effects, based on data from related compounds. According to a recent review of NPS stimulants, limited human data and case reports make risk prediction uncertain, so conservative handling in research settings is recommended.
Can 2‑CMC be used as a substitute for scheduled stimulants in research?
Some labs study 2‑CMC as part of panels designed to detect “replacement” stimulants that emerge when others are scheduled. However, each compound has unique properties and legal status, so it cannot simply be treated as a direct substitute for another stimulant.
Which other research chemicals are often ordered together with 2‑CMC?
Customers working on stimulant or NPS panels often also order NEP, 3‑MMC, methylone or dissociatives like 2‑FDCK for broader analytical coverage. This supports method validation across several chemical classes.
Where can professionals learn more about 2‑CMC and related substances?
Technical information can be found in forensic monographs such as the chloromethcathinone report from CFSRE, along with reference entries on sites like DrugBank, Cayman Chemical, TripSitter and PsychonautWiki. These sources provide chemical, pharmacological and regulatory context for researchers.
Call to action
If your laboratory requires high‑purity 2‑CMC (2‑Chloromethcathinone) research material alongside standards such as 3‑MMC, methylone or 2‑FDCK, contact our team through the Davechemicals.com official website. Share your country, institutional affiliation and intended analytical use so we can advise on availability, documentation and compliant shipping options.



Reviews
There are no reviews yet.