Buy 4-AcO-DET FUMARATE

Buy 4-AcO-DET FUMARATE

4-AcO-DET, also known as 4-acetoxy-N,N-diethyltryptamine, ethacetin or ethylacybin, is a synthetic tryptamine structurally related to psilocin and DET. It belongs to the 4‑substituted indole tryptamines, where an acetoxy group is attached at the 4‑position of the indole ring and the side chain carries a diethylamino group. Buy 4-AcO-DET FUMARATE

 What is 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 ❓

Structurally, 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) is regarded as the acetate ester analogue of 4‑HO‑DET (4‑hydroxy‑DET) and is expected to act as a pro‑drug for the corresponding 4‑hydroxy metabolite in biological environments. According to Trispsit style harm‑reduction resources and PsychonautWiki, this compound has been discussed as a rare, psilocin‑like tryptamine that appears primarily in specialist research contexts rather than mass consumer markets.

At Davechemicals.com, our 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 is supplied exclusively for research, analytical and forensic method development. For complementary reference materials within the same broad domain of experimental tryptamines and analogues, research teams often review options such as dipropyltryptamine DPT, 4-AcO-DET fumarate, and 4-AcO-DMT fumarate to build comparative data sets.

How does 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) fit within the tryptamine family

From a medicinal chemistry and pharmacology perspective, 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) sits in the same conceptual cluster as psilocin analogues such as 4‑AcO‑DMT and 4‑HO‑DET. Experimental work in animals suggests that substituted tryptamines including 4-acetoxy-N,N-diethyltryptamine produce discriminative stimulus effects similar to classical psychedelics like DOM in rat models, which indicates potential serotonergic activity at 5‑HT2A receptors.

Cardiac safety has been a particular research topic. A preclinical study investigating 4-AcO-DET and 4‑HO‑MET reported prolonged QT intervals in rats and inhibition of hERG potassium channels in vitro, which points to cardiotoxic potential at higher concentrations. Laboratory teams using 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) in in vitro or ex vivo models therefore treat it as a high‑risk research chemical that demands careful concentration control, appropriate risk assessments, and robust containment protocols.

For broader context on synthetic tryptamines and receptor pharmacology, many research groups consult reference platforms such as DrugBank, Drugs.com and Wikipedia alongside niche resources like PsychonautWiki and TripSit. These sources help build a rounded picture of the risk profile around 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5, even where formal clinical data are sparse.

Chemical profile of 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5

According to open chemical databases and secondary literature, 4-AcO-DET features the following profile.

All data below are provided strictly for informational and research‑planning purposes. Laboratory teams should confirm exact specifications from the product certificate of analysis at purchase.

Table 1. Research profile of 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5

For targeted comparison across tryptamines and psychoactive research materials, many labs construct panels that mix 4-AcO-DET with compounds such as 5-MeO-DMT, 5-MeO-MiPT and mescaline analogues like methallylescaline or allylescaline for cross‑platform receptor profiling.

Why laboratories buy 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 for research

Professional research teams in the UK, USA, Germany, Australia, and Asia who work with complex psychoactive scaffolds usually have practical reasons for adding 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 to their catalogue.

Key research motivations include:

• Receptor binding and functional assays
  • In vitro work can explore the serotonergic profile of 4-AcO-DET, particularly at 5‑HT2A and related receptors, alongside more established analogues.
• Metabolic and toxicology models
  A 2024 LC‑HRMS/MS study followed 4-AcO-DET metabolism in human liver S9 fractions and zebrafish larvae, identifying multiple metabolites and subtle cytotoxicity signals, which adds depth to forensic toxicology and risk assessment.
• Cardiac safety concern screening
  As noted earlier, rat ECG and hERG assays suggest that 4-AcO-DET can prolong QT intervals and inhibit cardiac potassium channels, which is of direct relevance to early safety screening.

Because 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) behaves as a rare and relatively data‑poor tryptamine, analytical chemists often pair it with more established comparators such as ketamine, N-ethyl ketamine, or dissociatives like 2-FDCK and deoxymethoxetamine when building broad LC‑MS libraries.

4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 at Davechemicals.com 🧪

Our position is simple. Research labs need consistent, clearly specified materials, with no marketing fluff and no ambiguity. 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) is supplied with that philosophy in mind.

Key laboratory‑facing characteristics

• High assay purity
  Each batch of 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 is supplied with a certificate of analysis, listing assay purity, residual solvents, water content and other QC parameters.
• Clear labelling and documentation
  Packaging is clearly labelled as “For research purposes, not for human consumption” in line with the site‑wide position of Davechemicals.com. Safety data sheets and handling notes are shared where available.
• Discreet, research‑oriented logistics
  Orders are fulfilled to registered research entities, not casual buyers. Our catalogue spans analytical standards as varied as carfentanil for sale, fentanyl powder for sale, U-47700 and niche cannabinoids such as JWH-018 and SGT-151, which means logistics are geared toward serious, specialist buyers.

Comparison table: 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) vs selected tryptamine research products

To support study design, many teams compare 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) with adjacent compounds.

Table 2. Positioning 4-AcO-DET among selected research tryptamines

This sort of panel helps pharmacology teams in the UK, USA, Germany, Australia, and Asia look at how 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) sits within a wider receptor and toxicity map, not as a standalone outlier.

Safety, toxicity and regulatory context for 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine)

There is no sugar‑coating the risk profile. 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 is a designer tryptamine with limited human data, and preclinical work has already raised concern about cardiotoxicity. A 2020 study reported QT interval prolongation and hERG channel inhibition in models exposed to this substance, which are classical warning signs of pro‑arrhythmic potential.

A more recent analysis combining human liver S9 fractions and zebrafish larvae expanded on the metabolism and cytotoxicity profile of 4-AcO-DET, again emphasising that such compounds fit squarely into the high‑risk new psychoactive substance category. From a risk management point of view, that means:

• Strict adherence to research‑only handling protocols.
• No direct contact without appropriate PPE and engineering controls.
• No off‑label or non‑laboratory use.

Regulatory status varies significantly by jurisdiction and can change rapidly, so any laboratory considering 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) must confirm its current legal position locally using primary legislation and government schedules. According to NPS reviews and harm-reduction resources, analogues of psilocin and DET are being increasingly caught by analogue or blanket bans around the world.

For laboratories that need alternative functional standards or adjuncts for their psychoactive panels, our catalogue also includes products such as ibogaine, 1P-LSD, and stimulant cathinones like 3-MMC, 4-MMC analogues such as 4-MPD and 4-METMP, which are also reserved for non‑clinical research.

Handling 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 demands strict research-only protocols and appropriate safety controls.

Buying 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 at Davechemicals.com 🛒

Our site is aimed at research buyers, not casual explorers. When laboratories buy 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 online at Davechemicals.com, they typically do so as part of a structured program that may also involve:

• High‑potency opioids for toxicology panels such as etonitazene, isotonitazene, protonitazene and metonitazene.
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Researchers who need tailored advice on product availability, shipping routes or documentation can reach out through Davechemicals.com Contact for a direct line to the team.

Table: Practical research checklist for 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine)

Table 3. Lab checklist before using 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5

This type of checklist keeps project teams aligned and reduces the chance of shortcuts with substances as sensitive as 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine).

FAQs: What is 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5?

1. What is 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) used for in research

4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 is used as a reference material in studies that investigate serotonergic tryptamines, including receptor binding, metabolism, and toxicity. It is not an approved medicine and is not used clinically or as a supplement.

2. Is 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) legal to buy

Legal status differs between countries and can shift as new psychoactive substance laws evolve, with many jurisdictions using analogue or blanket bans that can capture compounds like 4-AcO-DET. Research buyers must check their local legislation and, if needed, consult legal professionals before arranging supply.

3. Is 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) safe

Preclinical data suggest that 4-AcO-DET carries cardiotoxic risks, including QT interval prolongation and hERG channel inhibition at certain doses in animal and cell models. No reputable authority treats it as safe for human use, so it is restricted to controlled research environments with strict safety protocols.

4. How does 4-AcO-DET compare to 4-AcO-DMT

Both 4-AcO-DET and 4-AcO-DMT are 4‑acetoxy tryptamines, but they differ in the N‑substitution, diethyl versus dimethyl respectively, which influences potency and pharmacology. Animal discrimination studies indicate both compounds produce DOM‑like psychedelic cues, though potency rankings and side‑effect patterns are not identical.

5. Where can laboratories source 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5

Qualified research entities can obtain 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) and related analytical standards through specialist suppliers such as Davechemicals.com, which focuses on materials for non‑clinical research and analytical method development. Our broader selection includes tryptamines, dissociatives, synthetic cannabinoids and opioid standards, all labelled “for research purposes, not for human consumption”.

Key takeaways on 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5

• 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) is a synthetic tryptamine, structurally close to psilocin analogues, and studied mainly in laboratory settings.
• Preclinical literature flags notable cardiac and toxicity concerns, which means it belongs firmly in the high‑caution, research‑only category.
• For laboratories in the UK, USA, Germany, Australia and across Asia, 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 works best as one component of a broader analytical and pharmacological panel sourced through dedicated research suppliers such as Davechemicals.com.

If your lab needs 4-AcO-DET (4-acetoxy-N,N-diethyltryptamine) CAS 1135424-15-5 as part of a structured research program, review our tryptamine and analytical standard range starting with 4-AcO-DET fumarate, 4-AcO-DMT fumarate, and DPT, then reach out via Davechemicals.com Contact to discuss availability, documentation, and shipping routes tailored to your jurisdiction.